Shanghai East Hospital
Renji Hospital
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Tumor Therapy China

The Clinical Application of Stem Cells in Shanghai

In recent years, a variety of cell biology including the dendritic cell & cytokine-induced killer cells(DC-CiK);nature killer cells(NKC); CTL; autologous bone marrow mesenchymal stem cells(BMSC) and umbilical cord mesenchymal stem cells(UMSC) have been completed in nearly 500 cases, and cells with stable quality have good clinical safety. Related diseases and patients have gained significant clinical efficacy and benefit.

Product Features Treatment of diseases
Autologous bone marrow (BMSC) 1. Derived from autologous bone marrow, non-medical ethics
2. Easily amplification by culture, suitable for clinical application and production
3. Differentiation to a variety of tissues
4. Supported hematopoiesis
Ischemic heart disease
Cerebrovascular disease
Peripheral vascular disease
Spinal Cord Injury
Early cirrhosis
Multiple sclerosis
Femoral head necrosis
Repair organs
Umbilical cord derived (UMSC) 1. Derived from umbilical cord tissue, no ethical issues
2. Easily amplification by culture, suitable for clinical application and production
3. Differentiation to a variety of tissues
4. Low immunogenicity
5. Support of hematopoiesis and immune regulation
Aplastic anemia
Diabetes and diabetic foot
others as above
Neural stem cells(NSC) 1. Derived from healthy artificial labor embryos
2. A large number of passages, suitable for clinical application and production
3. Specific for nervous system diseases
Cerebral palsy
Spinal Cord Injury
Alzheimer's disease
Cerebellar atrophy
Parkinson's disease
Sequelae of stroke
Lateral sclerosis muscular dystrophy
Epidermal stem cells(ESC) 1. Epidermal stem cells specifically
2. Cells in relative naïve & undifferentiated state
3. High proliferative capacity, suitable for clinical application and production
Diabetic Foot
Wound healing
Anti-aging facial wrinkles
Dendritic cells & cytokine induced killer cells(DC-CiK) 1. Specific tumor cell killing and efficient non-specific tumor suppressor activity
2. Releasing a large number of cytokines
3. Regulating immunity and effectively improving the quality of life
4. Removing small lesions, delaying recurrence and metastasis and prolonging the span of life
5. Enhancing the sensitivity of chemotherapy and the overall therapeutic effect
Various malignant tumors
Systemic lupus erythematosus
Autoimmune hepatitis

Mesenchymal Stem Cells

Mesenchymal stem cells are pluripotent stem cells. Experimental results show: mesenchymal stem cells differentiate into bone cells, cartilage cells, fat cells, muscle cells, nerve cells and other types of cells. Currently, they have been isolated and cultured from human bone marrow, umbilical cord blood, fat, cartilage, liver and other tissues. The cells can be treated with multiple cells loss or functional disorders through autologous transplantation.

  • Keratonosus
  • Ischemic heart disease
  • Lower limb ischemia
  • Orthopedics
  • Nervous system disease
  • Skin beauty
  • Liver
  • Tumor
Stem Cells

Human Retinal Pigment Epithelial Cells (hRPE)

Stem Cells The cells derived from adult eye retinal pigment epithelium, are the best ones in treatment of Parkinson's disease. Although the cells are allogeneic, but experiments show that transplant into the head will not lead to immune rejection. The cell should be transplanted into a suitable target through precise stereotactic brain orientation operation. We have developed a specific tracer, which can observe by PET imaging whether the cell is survival, takes effect or not.

  • Parkinson's disease
  • Proliferative vitreoretinopathy,PVR
  • Age-related macular degeneration,ARMD

Neural Stem Cells

Stem Cells Neural Stem Cells are a kind of pluripotent stem cells, which can differentiate three kinds of primary cells into nervous system, including neurons, glial cells and oligodendrocytes. The cells can get from human neural tissue. We also have developed the method of getting neural stem cells from autologous brain tissue for autologous neural stem cell therapy.

  • Acute Spinal Cord Injmy, ASCI
  • Cerebral embolism
  • Post-traumatic brain syndro